About Masese Consulting Group LLC

Rigor, Evidence, & Operational Impact

Masese Consulting Group LLC bridges complex epidemiological data, implementation science, and health system strategy to drive sustainable population health outcomes.

Leadership & Principal Advisory

Edwin Masese Machine, DrPH, MPH
Principal Consultant & Founder

Dr. Edwin Masese Machine brings over 20 years of global experience bridging epidemiological research, health systems strengthening, and executive implementation strategy across public agencies, academic medical centers, and international initiatives.

His career spans managing high-profile Public-Private Partnerships (PPP) funded by ExxonMobil, serving as a Technical Advisor for the CDC Foundation on Bloomberg Philanthropies’ Data for Health initiative, and leading large-scale HIV/AIDS and TB clinical implementation strategies across Sub-Saharan Africa and the Pacific. His operational track record includes spearheading electronic medical record (EMR) system rollouts across clinical networks serving over 7,000 patients and generating real-world evidence (RWE) to guide national health policy formulation.

An accomplished academic scholar-practitioner, Dr. Machine has held faculty appointments with Baylor College of Medicine, Kabarak University, and the University of Papua New Guinea’s School of Medicine and Health Sciences. In his current academic appointment with the University of Houston’s Tilman J. Fertitta Family College of Medicine, he leads qualitative research and strategic planning initiatives to strengthen regional homeless response systems and health integration. He has trained health workforces through the Field Epidemiology Training Program (FETP), mentored postgraduate thesis research, and taught graduate biostatistics and epidemiology. He holds a Doctor of Public Health (DrPH) and a Master of Public Health (MPH) from the UTHealth Houston School of Public Health.

Core Technical Capabilities

Implementation Science

Translating evidence-based interventions into scalable clinical and public health delivery across complex, resource-constrained environments.

  • Framework Contextualization: Applying RE-AIM and CFIR models to adapt clinical protocols to local system capacity.
  • Workforce Enablement: Mentoring frontline healthcare teams and FETP fellows to improve delivery fidelity and patient retention.

Data Analytics & Informatics

Leveraging biostatistical rigor, population health analytics, and health informatics to guide resource allocation and executive decisions.

  • Health Systems Informatics: Leading end-to-end EMR deployments and multi-source surveillance data integration.
  • Real-World Evidence (RWE): Synthesizing population health datasets to inform national policy and executive strategy.

Program Evaluation & MERL

Designing mixed-methods evaluation protocols, performance tracking systems, and quality improvement feedback loops for health systems.

  • Mixed-Methods Evaluations: Executing multi-country program assessments (UNICEF, WHO) across clinical networks.
  • Performance Dashboards: Building logic models and CQI frameworks that align operational metrics with target health outcomes.

Driven by Evidence, Focused on Impact

Sustainable health system transformation requires more than theoretical design—it demands rigorous execution, adaptive learning, and actionable data strategy. Masese Consulting Group LLC partners with organizations committed to elevating population health through evidence-grounded solutions.

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